Inhibitory Effect of (Z)-5-(4-(2-Methoxyethoxy)benzylidene)-2-thioxothiazolidin-4-one on Tyrosinase in Yacon

doi:10.7506/spkx1002-6630-201209036

FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (9): 173-176.doi: 10.7506/spkx1002-6630-201209036

• Bioengineering • Previous Articles Next Articles

Inhibitory Effect of (Z)-5-(4-(2-Methoxyethoxy)benzylidene)-2-thioxothiazolidin-4-one on Tyrosinase in Yacon

CHEN Ling-juan1，TANG Xue-juan2，ZHAO Liang-zhong2,*，LIU Jin-bing2

(1. College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410009, China； 2. Department of Chemical Biotechnology and Engineering, Shaoyang University, Shaoyang 422000, China)

Online:2012-05-15 Published:2012-05-07

Abstract

Abstract: The inhibitory effect of (Z)-5-(4-(2-methoxyethoxy)benzylidene)-2-thioxothiazolidin-4-one (MBTO) on tyrosinase in yacon was studied by spectrometrically. The results showed that MBTO had excellent inhibitory effect on tyrosinase in yacon. The optimal inhibitory concentration, time and temperature, as determined by one-factor-at-a-time design, were 30μmol/L, 210 s, and 30 ℃, respectively. The results of 3-variable, 3-level orthogonal array experiments showed that the best inhibition results were obtained by treatment with 30.0μmol/L MBTO at pH 7.5 and 30 ℃ for 330 s, yielding an inhibitory rate as high as 84.24%.

Key words: (Z)-5-(4-(2-methoxyethoxy)benzylidene)-2-thioxothiazolidin-4-one, yacon, tyrosinase, orthogonal array design

CLC Number:

CHENLing-juan，TANGXue-juan，ZHAOLiang-zhong，LIUJin-bing. Inhibitory Effect of (Z)-5-(4-(2-Methoxyethoxy)benzylidene)-2-thioxothiazolidin-4-one on Tyrosinase in Yacon[J]. FOOD SCIENCE, 2012, 33(9): 173-176.

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Inhibitory Effect of (Z)-5-(4-(2-Methoxyethoxy)benzylidene)-2-thioxothiazolidin-4-one on Tyrosinase in Yacon

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