Effect of Lactobacillus plantarum F1208 on Gastrointestinal Functions in Constipated Rats

doi:10.7506/spkx1002-6630-201313051

Abstract

Abstract:

Purpose: The objective of this study is to evaluate the regulatory effect of Lactobacillus plantarum F1208 on
gastrointestinal functions in constipated rats. Methods: Male Wistar rats were randomly divided into health group, constipation group,
senna group, and Lactobacillus plantarum high-, middle- and low-dosage groups. A rat model of loperamide hydrochloride-induced
constipation was established. Each group was treated with corresponding drugs at 2 mL/(kg•d) for 7 days. During the experiment, feed
intake, water intake, body quality increase, fecal number and water content, live bacterial count in feces and gastrointestinal transit
ratio were monitored. Results: The administration with Lactobacillus plantarum F1208 for 7 days in constipated rats significantly
improved the feed intake and water intake, promoted the growth and development of rats, increased the number and water content
of feces within 24 hours, restrained the growth of intestinal bowel enterobacter and enterbacteriaceae, and improved gastrointestinal
transit ratio. Conclusion: Lactobacillus plantarum F1208 has improved gastrointestinal functions in constipated rats.
Conclusion: Lactobacillus plantarum F1208 has improvement gastrointestinal function in constipation rats.

Key words: Lactobacillus plantarum, constipation, gastrointestinal function, rats

CLC Number:

R37
TS201.3

PENG Zhi-rong1,2，LIU Xiao-mei1,2，NI Xue-qin1,3,*，YANG Jie1，ZOU Zhao-yong1，QIU Chun-hong1，ZENG Dong1,3. Effect of Lactobacillus plantarum F1208 on Gastrointestinal Functions in Constipated Rats[J]. FOOD SCIENCE, doi: 10.7506/spkx1002-6630-201313051.

[1]	WANG Jing, HUANG Qingchen, GAO Minyue, ZHU Xiaopan, CHEN Zitong, WANG Shaokang, SUN Guiju. Preventive Effect of Forsythin from Forsythia suspensa Leaves on Obesity Induced by High-Fat Diet in Rats [J]. FOOD SCIENCE, 2021, 42(9): 85-90.
[2]	LI Xinrui, ZHAO An, FAN Xiaopiao, GAO Wenwen, SHANG Jiacui, ZHAO Penghao, ZHAO Le, ZHOU Xue, MENG Xiangchen. Prokaryotic Expression and Purification of PurR and PurL from Lactobacillus plantarum KLDS1.0391 and Their Interaction with Bacteriocin Synthesis Promoter [J]. FOOD SCIENCE, 2021, 42(6): 75-81.
[3]	WU Lingfeng, WEI Shuang, CHEN Ying, DU Minjie, LIU Sixin, WANG Lu, LI Congfa. Effects of Fructooligosaccharides on the Chemical, Microbiological and Antioxidant Properties of Tamarind (Tamarindus indica L.) Juice Fermented by Lactobacillus plantarum A33 [J]. FOOD SCIENCE, 2021, 42(4): 122-129.
[4]	LEI Wenping, ZHOU Hui, CHEN Qi, ZHOU Xingrong, WU Kun, WANG Jiaqi, LIU Chengguo. Screening and Identification of Probiotics with Hyaluronidase Inhibitory Activity in Vitro [J]. FOOD SCIENCE, 2021, 42(2): 151-157.
[5]	ZHAO Le, ZHANG Xiaotong, LIU Lijun, XIE Shuiqi, JIN Qiwen, MENG Xiangchen. Effects of Amino Acids on Growth and Bacteriocin Synthesis of Lactobacillus plantarum KLDS1.0391 [J]. FOOD SCIENCE, 2021, 42(18): 37-44.
[6]	XIAO Ye, YE Jingqin, LI Xiaochen, LI Xiaohui, SHI Wenzheng, LU Ying. Effect of Lactobacillus plantarum on Reducing the Immunological Activity of Tropomyosin [J]. FOOD SCIENCE, 2021, 42(18): 95-102.
[7]	ZHAO Xiao, XU Jinghan, CUI Dongying, XU Jinzhao, LIU Yang, TENG Guoxin, XU Xiaoxi. Positive Regulation of Lactoferrin on Gut Micro-Ecology of Rats with Inflammatory Bowel Disease [J]. FOOD SCIENCE, 2021, 42(13): 136-142.
[8]	GAO Zhaojian, HUANG Lianghao, DING Feihong, ZHAO Yifeng, CHEN Teng. Characterization of Novel Broad-Spectrum Bacteriocin Produced by Lactobacillus plantarum from Pickles [J]. FOOD SCIENCE, 2021, 42(10): 171-177.
[9]	FANG Laishan, LAI Qiang, ZHONG Zemin, HUANG Yumao. Sequence Analysis of an Endogenous Plasmid in Lactobacillus plantarum and Construction of a Shuttle Expression Vector Using It [J]. FOOD SCIENCE, 2020, 41(4): 118-124.
[10]	LU Zhou, DAI Yiqiang, Hafiz Abdul RASHEED, WU Han, XIA Xiudong, DONG Mingsheng. Antimicrobial Activity of Soy Whey Fermented by Lactobacillus plantarum D1501 and Purification and Identification of Bacteriocin from It [J]. FOOD SCIENCE, 2020, 41(24): 117-124.
[11]	ZHANG Yuzhu, WANG Bingyi, ZENG Zi’ao, XU Ruoyun, LI Jun, FAN Mingtao, WEI Xinyuan. Effect of Culture Conditions on the Formation of Selenium Nanoparticles with Different Particle Sizes by Microbial Reduction Using Lactobacillus plantarum and Their Bioactivity Evaluation [J]. FOOD SCIENCE, 2020, 41(22): 119-126.
[12]	LIU Shuting, WANG Ying, WANG Zhihui, WANG Di, ZHANG Yanli, ZUO Zhaohang, WANG Haoyu, DENG Wei. Repairing Effect of Resistant Starch from Purple Speckled Kidney Beans (Phaseolus vulgaris) on Liver and Intestinal Barrier Injury in Rats with Hyperlipidemia [J]. FOOD SCIENCE, 2020, 41(21): 106-112.
[13]	LI Qiangkun, LIU Chenjian, LUO Yiyong, YANG En, LI Xiaoran. Effects of Different Fermentation Conditions on Folate Synthesis of Lactobacillus plantarum [J]. FOOD SCIENCE, 2020, 41(2): 114-118.
[14]	GUO Lidong, ZHANG Wenwen, LIU Yan, HUANG Mengling, MEN Yue, ZHANG Yanli, WANG Liqun. Isolation and Probiotic Properties of Lactobacillus plantarum HUCM115 from Traditional Pickled Chinese Cabbage [J]. FOOD SCIENCE, 2020, 41(18): 140-145.
[15]	LIU Yaoyao, LI Lu, LIU Tingting, ZHANG Shanshan, XUN Yiping, ZHU Hong, WANG Shijie, BIAN Yanqing, ZHAO Baohua. Effect of Lactobacillus plantarum Powder on Intestinal Mucosal Barrier Function in Obese Rats [J]. FOOD SCIENCE, 2020, 41(17): 153-160.

Effect of Lactobacillus plantarum F1208 on Gastrointestinal Functions in Constipated Rats

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments