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Recent Progress in the Preparation of Artificial Antigen of Mycotoxins

WU Chun-sheng, MA Liang, HU Yuan-yuan, ZHANG Yu-hao   

  1. 1. College of Food Science, Southwest University, Chongqing 400715, China; 2. Laboratory of Quality and Safety Risk Assessment
    for Agro-products on Storage and Preservations (Chongqing), Ministry of Agriculture, Chongqing 400716, China;
    3. Chongqing Special Food Programme and Technology Research Center, Chongqing 400716, China
  • Online:2014-03-15 Published:2014-04-04

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Abstract:

The main analytical techniques currently available for rapid detection of mycotoxins include enzyme-linkedimmunosorbent assay (ELISA) and gold-labeled immunochromatography. The synthesis of artificial antigen and the natureof antibodies are the most critical factors in rapid immunological detection of mycotoxins. This paper reviews the recentprogress at home and abroad in the preparation/synthesis of artificial antigens of mycotoxins as hazardous contaminantsof cereal and oil products. In addition, some existing problems and corresponding solutions are pointed out. This reviewwill hopefully provide a theoretical basis for preparing artificial antigens of small molecule contaminants and develop theantibodies with high affinity and specificity.

Key words: mycotoxin, hapten, artificial antigen, preparation