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Effect of Inulin-Supplemented Yogurt on Immune Organ Indexes and Serum Immunoglobulin in Mice

XIONG Zheng-wei, ZHENG Yun, LAN Yang, GOU Zhen-qiong, LIU Wei, DONG Quan   

  1. 1. College of Food Science, Southwest University, Chongqing 400715, China; 2. School of Biological and Chemical Engineering,
    Chongqing University of Education, Chongqing 400067, China
  • Online:2014-11-15 Published:2014-11-06

Abstract:

Feeding experiments were carried out on mice to research the effect of yoghurt with added inulin on spleen and
thymus indices, body weight and the serum levels of immunoglobulin (Ig) G, IgA and IgM. Inulin could stimulate the growth
of lactobacilli in yogurt. Compared with ordinary yogurt, inulin-fortified yogurt could improve the immune function of mice.
Correlation analysis showed that IgG and IgA were associated with the significant number of lactic acid bacteria in yogurt.
Thus, yogurt with added inulin had an enhanced effect on immune function by facilitating the growth of lactic acid bacteria.
Yogurt with 50 g/L inulin was the most effective in enhancing the immune function of mice.

Key words: inulin-supplemented yogurt, mice, spleen index, thymus index, serum immunoglobulin

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