Hypoglycemic Effect of Crude Polysaccharide Extract from Aralia chinensis on Diabetic Rats

doi:10.7506/spkx1002-6630-201513039

Abstract

Abstract:

Purpose: To observe the hypoglycemic effect of crude polysaccharides from Aralia chinensis roots (APC) on
experimental diabetic rats. Methods: A rat model of diabetes was induced through the injection of alloxan. Sprague-Dawley
(SD) rats were randomly divided into six groups: low, medium and high ACP dose groups, positive control group, blank
control group and diabetic model group. The mice in the treatment groups were administrated with APC for 4 consecutive
weeks, and then the changes in fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), total cholesterol (TC),
triglyceride (TG), high density lipoprotein (HDL) and low density liporotein (LDL) were determined. Results: ACP could
reduce the levels of FBG and HbA1c in diabetic rats, decrease the contents of serum TC and TG, significantly increase
HDL levels, and result in little change in LDL levels. Conclusion: ACP can effectively ameliorate the metabolism of blood
glucose and lipids in diabetic rats.

Key words: Aralia chinensis, crude polysaccharides, diabetes rats, hypoglycemia, serum lipid

CLC Number:

Q946.3

ZHAO Bo1,2, WANG Yifeng1,*, HOU Honghong1. Hypoglycemic Effect of Crude Polysaccharide Extract from Aralia chinensis on Diabetic Rats[J]. FOOD SCIENCE, doi: 10.7506/spkx1002-6630-201513039.

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Hypoglycemic Effect of Crude Polysaccharide Extract from Aralia chinensis on Diabetic Rats

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