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Progress in Research on the Antitumor Mechanisms of Plant Polyphenols Based on Proteomics

LI Yao1, LIAO Xia1, XIAO Xingning1, ZHANG Xiaoli1, LU Keke1, WU Surui2, MING Jian1,3,*   

  1. 1. College of Food Science, Southwest University, Chongqing 400715, China;
    2. Kunming Edible Fungi Institute, All China Federation of Supply and Marketing Cooporatives, Kunming 650223, China;
    3. Chongqing Engineering Research Center of Regional Food, Chongqing 400715, China
  • Online:2016-02-15 Published:2016-02-26

Abstract:

Proteomics, an important method for the large-scale study of cellular proteins, has been widely used for exploring
the molecular mechanisms of cancer, searching for biomarkers, and screening for new anticancer drugs. The antitumor
potential of plant polyphenols, as natural active substances, has been confirmed. This paper provides an overview of
proteomics and reviews recent progress in proteomic studies of the antitumor mechanisms of plant polyphenols, aiming to
provide a scientific basis for the application of plant polyphenols in health food and drugs.

Key words: plant polyphenols, proteomics, antitumor, molecular mechanism

CLC Number: