Abstract:

Nucleotides (NTs) are low-molecular-weight biological molecules crucial to biochemical processes. They play
an important role in maintaining the immune system, accelerating the proliferation of immune cells and the secretion of
cytokines. Although endogenous production serves as the major nucleotide source, evidence suggests that exogenous
sources, mainly dietary nucleotides, have more connection with immune system. This article reviews previous researches on
the effects of NTs on immune function.

Key words: exogenous nucleotides, immune function, inflammation