FOOD SCIENCE ›› 2017, Vol. 38 ›› Issue (13): 269-276.doi: 10.7506/spkx1002-6630-201713044

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A Review of Research on Lactic Acid Bacteria Food-Grade Vectors and Their Applications

WANG Yao, WEI Yunlu, LI Pinglan   

  1. Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China
  • Online:2017-07-15 Published:2017-07-11

Abstract: Lactic acid bacteria (LAB) are important probiotic microorganisms used in food fermentation industry. Molecularbiological manipulation of these microorganisms has great potential for the development of food industry and human health.Based on the characteristics of lactic acid bacteria and the development of molecular biology, this review aims at the basicprinciples of a food-grade vector system for LAB, the components of a food-grade plasmid, the strategies to construct andtransform a food-grade plasmid, and recent applications of food-grade plasmids. This review highlights that food-grademolecular biology could have a major positive impact on further development and application of LAB.

Key words: lactic acid bacteria, food-grade system, plasmid

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