FOOD SCIENCE ›› 2019, Vol. 40 ›› Issue (20): 332-337.doi: 10.7506/spkx1002-6630-20180827-295

• Safety Detection • Previous Articles     Next Articles

YANG Jinquan, HE Xiaomin, SHI Minfang, CHEN Hao, LI Yongrong, ZHU Youlin

YANG Jinquan, HE Xiaomin, SHI Minfang, CHEN Hao, LI Yongrong, ZHU Youlin   

  1. (1. Hubei Provincial Environmental Monitoring Center Station, Wuhan 430072, China;2. College of Science, Huazhong Agricultural University, Wuhan 430070, China; 3. College of Resources and Environment, Yangtze University, Wuhan 430100, China)
  • Online:2019-10-25 Published:2019-10-25

Abstract: An analytical method was established for the determination of bisphenol A (BPA) and bisphenol S (BPS) in drinking water by solid-phase extraction and ultra performance liquid chromatography-tandem mass spectrometry (SPE-UPLC-MS/MS). BPA and BPS from samples were enriched by an Oasis HLB SPE cartridge, eluted with methanol and concentrated with nitrogen. The analytes were separated on an C18 column with 1 mmol/L NH4F aqueous-acetonitrile as the mobile phase, and then analyzed by UPLC-MS/MS using multiple reaction monitoring (MRM) under the negative-ion mode. The limits of detection (LODs) of the method for BPA and BPS were 1.0 and 0.2 ng/L, respectively. The mean recoveries at three spiked levels of BPA ranged from 88.3% to 114.8%, with relative standard deviations (RSDs) of 10.0%–16.2%. The recoveries of BPS were 83.7%–98.2%, with RSDs of 5.9%–12.3%. The method was proved to be sensitive, accurate and efficient, and it was suitable for qualitative and quantitative analysis of BPA and BPS in drinking water.

Key words: bisphenol A, bisphenol S, ultra performance liquid chromatography-tandem mass spectrometry, drinking water, solid-phase extraction

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