Studies on Purification and Antitumor Activity of Fruit Polysaccharide Isolated from Chinensis Actinidia Planch.

Abstract

Abstract: A raw fruit polysaccharide (FP) was isolated from Chinensis Actinidia Planch. By using ion exchange chromatography, FP was separated into two parts, FP1 and FP2. The inhibitory effects of FP, FP1 and FP2 on the transplanted tumor cells of Sarcinoma 180 (S180) in mice were tested. The results showed that with the dosage of 150mg/kg FP2 could evidently reduce the tumor weight of S180, and the inhibitory rate reached 54.2%. The homogeneity of FP2 was proved by size exclusion chromatography. Paper chromatography showed that FP2 contained D-glucose, D-mannose and D-galactose.

Key words: Chinesis Actinidia Planch, polysaccharide, purification, anti-tumor activity

LU Dan, YU Li-Chao, YAO Shan-Jing. Studies on Purification and Antitumor Activity of Fruit Polysaccharide Isolated from Chinensis Actinidia Planch.[J]. FOOD SCIENCE, 2005, 26(2): 213-215.

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Studies on Purification and Antitumor Activity of Fruit Polysaccharide Isolated from Chinensis Actinidia Planch.

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