Protective effects of Cucurbitacin B on the Acute Liver Injury Induced by CCL4

FOOD SCIENCE ›› 2005, Vol. 26 ›› Issue (9): 524-526.

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Protective effects of Cucurbitacin B on the Acute Liver Injury Induced by CCL4

YANG Shi-Jie, CHANG You-Quan, ZHENG Li-Hua, WEI Zheng-Ren, QU Hong-Guang, CAO Shu-Gui

1.The Pharmacology of Basic Medical School of Jilin University;2.Key Laboratory of Molecular Enzymology and Engineering of Educational Ministry Jilin University;3. Jilin Normal Institute of Engineering and Technology

Online:2005-09-15 Published:2011-09-20

Abstract

Abstract: Objective: To observe the protective effects of Cucurbitacin B on the liver injery in mice and rats. Methods: The model of acute liver injury in mice and rats were induced by CCL4, the content of GPT, GOT, ALP, TP, TBIL in serum were measured.The change of liver histopathology were observed.Results each group can reduce the content of GPT, GOT, ALP, TBIL in serum. Conclusion: Cucurbitacin B has the protective effects on the liver injury induced by CCL4.

Key words: melon vines effective part, tetrachloride, acute liver injury

YANG Shi-Jie, CHANG You-Quan, ZHENG Li-Hua, WEI Zheng-Ren, QU Hong-Guang, CAO Shu-Gui. Protective effects of Cucurbitacin B on the Acute Liver Injury Induced by CCL4 [J]. FOOD SCIENCE, 2005, 26(9): 524-526.

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Protective effects of Cucurbitacin B on the Acute Liver Injury Induced by CCL4

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