Abstract: Objective: 67 local strains isolated from food samples and egg samples and 4 type strains were analyzed by random amplified polymorphic DNA(RAPD). It was not only related with the homology analysis of 29 Serotype of Salmonella, but also provided basis for the epidemiological traceability of food-borne disease and the controlling of the disease. Method: 10 bases primer were selected in the use of the RAPD analysis of 71 Salmonella. The fingerprinting of RAPD result was analyzed by NTSYS- pc2.10e. Result: When the rate of correlation is 0.7, 71 Salmonella can be divided into 7 groups. The group of most number has 54 strains. When the rate of correlation is 0.9, 71 Salmonella can be divided into 26 groups. The group of most number has 18 strains. When the rate of correlation is 1.0, 9 groups can reach the level. The group of most number has 11 strains. The result of RAPD analysis agrees with the analysis of serological test at the level of 90 percent. Conclusion: the technique of RAPD can be used to the epidemiological traceability of food-borne disease.

Key words: Salmonella, local strains, RAPD, clustering analysis, homology