Cytotoxicity of Ursolic Acid in vitro and Its Inhibition Effect on Cytotoxicity of Acrylamide

Abstract

Abstract: Objective:To evaluate the cyotoxicity of diffirent doses ursolic acid and its inhilition effect on cytoxicity of acrylamide. Methods:Diffirent test matters were loaded on the culture plate.The viability of cells was evaluated by MTT assay to investigate cell proliferation. Optical density(OD) was measured by a spectrophotometer at 490 nm. Then the cytotoxicity grade was evaluated according to the means of cell proliferation and the statistical significance. Result:Ursolic acid is innoxious to the tested cells. It has great inhibition effect on cyotoxicity of acrylamide.

Key words: ursolic acid, cytotoxicity, acrylamide

HUANG Yu-Ai, WANG Fei, SHEN Xue, WANG Hao, GUAN Shuang, LU Jing. Cytotoxicity of Ursolic Acid in vitro and Its Inhibition Effect on Cytotoxicity of Acrylamide[J]. FOOD SCIENCE, 2008, 29(8): 594-596.

[1]	ZOU Zhaojia, ZHENG Jie, HUANG Caihuan, LIU Fu, OU Shiyi. Preparation and Cytotoxicity of Acrolein-Alanine Adduct [J]. FOOD SCIENCE, 2021, 42(9): 1-6.
[2]	WANG Tengfei, SUN Dawen, PU Hongbin, WEI Qingyi. Progress on Strategies for Inhibition of Acrylamide Formation in Foods [J]. FOOD SCIENCE, 2021, 42(17): 333-342.
[3]	OUYANG Yu, ZHAO Kuoquan, FENG Yingna, ZHANG Liang, WU Qian. A Review of the Biological Activities and Potential Health Risks of Maillard Reaction Products [J]. FOOD SCIENCE, 2021, 42(17): 350-362.
[4]	LI Linqiong, HONG Jing, ZHANG Lijun, GAO Yulong. Effect of Acid Stress on Acid Resistance, Cell Membrane and Membrane Protein of Salmonella typhimurium [J]. FOOD SCIENCE, 2021, 42(15): 27-36.
[5]	LIU Lichun, JIANG Yujie, SHEN Mingyue, XIE Mingyong, NIE Shaoping. Inhibitory Effect of Natural Antioxidants on the Formation of Thermal Processing Hazards in Red Braised Pork [J]. FOOD SCIENCE, 2021, 42(15): 50-57.
[6]	LI Tong, WU Siqi, CAO Xin, SONG Jingyi, ZHANG Hongxing, XIE Yuanhong, JIN Junhua. Screening for Antioxidant Probiotics and Their Protective Effect on Oxidative Damage Induced by Acrylamide in Intestinal Epithelial Cells [J]. FOOD SCIENCE, 2020, 41(2): 173-180.
[7]	JIANG Guoyong, LEI Aitong, YANG Ying, YU Qiang, XIE Jianhua, CHEN Yi. Protective Effect of Ganoderma atrum Polysaccharides against Acrylamide-Induced Liver Injury in Rats [J]. FOOD SCIENCE, 2020, 41(1): 121-126.
[8]	GONG Xiao, TANG Yali, LU Lixin, QIU Xiaolin, WANG Jun. Effects of TOCNs and Cationic Polyacrylamide on Properties of Sodium Carboxymethyl Cellulose Film [J]. FOOD SCIENCE, 2019, 40(4): 1-6.
[9]	YUAN Yue, ZHAO Yongqiang, YANG Xianqing, LI Laihao, WU Yanyan, WEI Ya, CEN Jianwei. Cryoprotective Mechanism of Epigallocatechin Gallate on Frozen Nile Tilapia (Orechromis niloticus) Surimi [J]. FOOD SCIENCE, 2019, 40(24): 79-85.
[10]	ZHao Sijia, li Rui, LIU Tong, sun Hongyang, shen Yu, zhao Xiaoduo, SHANG Jiaqi, shao Meili. Comparative Study on the Stability of Five Strains of Lactic Acid Bacteria Adsorbing Acrylamide [J]. FOOD SCIENCE, 2019, 40(24): 151-156.
[11]	CHEN Juhua, JIAO Linshu, XIE Yajuan, LU Zhaoxin, ZHANG Chong, Lü Fengxia. Cloning, Expression and Characterization of a Novel Type I L-Asparaginase from Bacillus licheniformis and Its Application in Reduction of Acrylamide in French Fries [J]. FOOD SCIENCE, 2019, 40(22): 20-26.
[12]	CAO Yungang, MA Wenhui, AI Nasi, YAN Linlin, ZHAO Qianqian, MIN Hongwei, BAI Xue, HUANG Junrong. CAO Yungang, MA Wenhui, AI Nasi, YAN Linlin, ZHAO Qianqian, MIN Hongwei, BAI Xue, HUANG Junrong [J]. FOOD SCIENCE, 2019, 40(20): 21-27.
[13]	SHAN Jinhui, CHEN Jiwang, LIU Yan, WANG Haibin, XIA Wenshui, Youling L. XIONG. Prediction of Acrylamide Content in Fried Battered and Breaded Fish Nuggets Using Artificial Neural Network [J]. FOOD SCIENCE, 2019, 40(16): 249-255.
[14]	WANG Wenjuan, CAI Xiaofang, TANG Jie, ZHANG Xirong, FENG Di. Application of in Vitro Bioassays in Safety Evaluation of Food Contact Materials: A Review [J]. FOOD SCIENCE, 2019, 40(15): 277-284.
[15]	LI Tianjiao, ZHANG Yongjie, WANG Zilong, LIU Ying, LIANG Hui. Protective Effect of Lactobacillus casei on Acrylamide-Induced Intestinal Injury in Rats [J]. FOOD SCIENCE, 2018, 39(9): 121-126.

Cytotoxicity of Ursolic Acid in vitro and Its Inhibition Effect on Cytotoxicity of Acrylamide

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments