Abstract: Objective: To study on anti-fatigue effect of Eucommia ulmoides male flower tea on mice. Method: Mice were randomly assigned to control group, low dose, middle dose and high dose experimental groups according to their body weights. Eucommia ulmoides male flower tea was administered in experimental groups with doses of 130, 260, 520 mg/kg respectively, and the control mice were given water. After 30 days, the swimming test were carried out and the death time was observed and recorded, after the mice swimming for a period blood was taken for determining serum lactic-acid, blood urea nitrogen (BUN) and glycogen. The liver was taken for determining glycogen. Results: Eucommia ulmoides male flower tea can significantly prolong swimming time, reduce BUN level, increase liver glycogen storage and accelerate lactic-acid clearance after swimming. Conclusion: Eucommia ulmoides male flower tea can alleviate physical fatigue of mice.

Key words: Eucommia ulmoides male flower tea (EUMFT), anti-fatigue, blood urea nitrogen (BUN), serum lactic-acid, glycogen