Abstract: To investigate the preventive and curative effects of rape bee pollen on alcoholic liver disease (ALD) of rats,ALD models of rats were established by intragastric infusion of 42° liquar. After four weeks,the activities of serum ALT,AST,MDA,GSH-ST,GSH and TG were determined. Meanwhile,the pathological changes of liver were observed under light microscope after HE staining. Compared with that in the control group,the level of serum TG significantly increases,and the content of GSH-ST significantly decreases due to alcoholic injury. The groups of rape bee pollen extract except group C can significantly increase the level of GSH-ST in blood serum. The group of B,Cand D can decrease the level of TG in blood serum. The group of B,and C can increase the level of GSH in blood serum. The results showed that rape bee pollen and its different extracts can reverse the damage caused by alcohol,especially for the group C,D and E.

Key words: alcoholic liver disease (ALD), rape bee pollen, the extracts of rape bee pollen