Abstract: Selenium was enriched and bio -converted by Lentinus edodes mycelia by means of submerged fermentation The content of Selenmm was enriched to 225μg /g.The existing state of Selenium w as con- verted from inorganic substance to o rganic substance,and the content of amino acid was high er than that of contrast.The powdered milk made f rom Se -enriched Lentinusedodes mycelia was rich in nutrition and became a functional food because of i ts high content of Selenium and polysaccharide.

Key words: submerged fermentation, Lentinusedodes, Se -enriched, powdred milk