Abstract:

The biomass production of edible and medicinal fungi and the synthesis of secondary metabolites may be
significantly promoted by adding the suitable concentration of additives to the fermentation substrate. This paper reviews
the effects of some exogenous additives such as traditional Chinese medicines, growth factors, grease-like materials and
signaling molecules on submerged fermentation of edible and medicinal fungi as well as the underlying mechanism of
metabolism regulation, which will hopefully provide a theoretic foundation for further research and development of edible
and medicinal fungi.

Key words: exogenous additives, edible and medicinal fungi, submerged fermentation, metabolism regulation