FOOD SCIENCE ›› 2018, Vol. 39 ›› Issue (21): 149-154.doi: 10.7506/spkx1002-6630-201821022

• Nutrition & Hygiene • Previous Articles     Next Articles

Sport Fatigue-Alleviating Effect of Ophiocordyceps lanpingensis

KONG Na1, YU Hong2,3, ZHANG Yanyan1, GE Feng1,3,*   

  1. 1. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China; 2. Yunnan Herbal Laboratory, Institute of Herb Biotic Resources, Yunnan University, Kunming 650091, China; 3. The Research Center of Cordyceps Development and Utilization of Kunming, Kunming 650091, China
  • Online:2018-11-15 Published:2018-11-21

Abstract: Objective: To investigate the anti-fatigue effect of Ophiocordyceps lanpingensis (OL) in mice. Methods: Mice were randomly divided into five groups: negative control (orally administered with distilled water), positive control (administered with 600 mg/(kg·d mb) of American ginseng) and OL low-, medium- and high-dose (gavaged with OL powder at doses of 450, 900, and 1 800 mg/(kg·d mb) , respectively) groups. After administration for 30 days, the weight-loading swimming time as well as blood lactic acid, blood urea nitrogen (BUN), glycogen (LG) and antioxidant enzyme activities and other fatigue-related blood parameters in the mice were determined. Results: Ophiocordyceps lanpingensis could increase the weight-loading swimming time of mice at all doses (P < 0.05); the mice from the middle- and high-dose group showed significantly reduced levels of BUN after exercise (P < 0.05); the mice from the high-dose group and the positive control group could significantly improve LG level (P < 0.05). Meanwhile, Ophiocordyceps lanpingensis improved blood hemoglobin and blood sugar levels, increased the activity of antioxidant enzymes, and reduced blood malondialdehyde content. Conclusion: Ophiocordyceps lanpingensis has an anti-fatigue effect in mice.

Key words: Ophiocordyceps lanpingensis, anti-fatigue, anti-oxidant, Ophiocordyceps lanpingensis

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