Abstract:

The effect of polysaccharides extracted from blueberry (BPs) on exhaustive swimming time and related
physiological indexes in aged mice induced by D-galactose was investigated. Mice were randomly divided into normal
control group, aged model group, low-dose BP group, middle-dose BP group, and high-dose BP group. The aged model
was induced by D-galactose at a dose of 100 mg/(kg·d) for 60 consecutive days. After the administration of BPs for 20
consecutive days, the exhaustive swimming time and fatigue indexes were determined. The results showed that BPs could
extend the exhaustive swimming time, decrease the contents of BUN, BLA and MDA, and obviously increase the reservation
of HG, MG, SOD and LDH. To conclude, BPs have a good anti-fatigue effect. This study may provide theoretical evidence
for the development of anti-fatigue drugs from BPs.

Key words: blueberry polysaccharides, D-galactose, anti-fatigue effect, exhaustive swimming time