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茶叶中吡咯里西啶生物碱检测技术、污染水平及健康风险研究进展

韩浩蕾1,姜长岭1,王晨1,2,3,刘新1,鲁成银1,陈红平1   

  1. 1. 中国农业科学院茶叶研究所
    2. 农业农村部茶叶产品质量安全风险评估实验室(杭州)
    3. 农业农村部茶叶质量安全控制重点实验室
  • 收稿日期:2020-07-08 修回日期:2021-06-25 出版日期:2021-09-15 发布日期:2021-09-24
  • 通讯作者: 陈红平 E-mail:thean27@tricaas.com
  • 基金资助:
    国家自然科学基金面上项目;中国农业科学院创新团队茶叶质量与风险评估团队;现代农业产业技术体系建设专项;国家农产品质量安全风险评估项目

Pyrrolizidine Alkaloids in Tea: A Review of Analytical Methods, Contamination Levels and Health Risk

  • Received:2020-07-08 Revised:2021-06-25 Online:2021-09-15 Published:2021-09-24
  • Contact: Chen -Hongping E-mail:thean27@tricaas.com

摘要: 吡咯里西啶生物碱(Pyrrolizidine Alkaloids,PAs)是一类植物次级代谢产物,其中不饱和PAs及大部分PAs的氮氧化物(pyrrolizidine alkaloid N-oxides,PANO)具有多种毒性作用。PAs已被发现广泛存在于各类茶叶中,且成为我国茶叶出口受阻的主要污染物之一。本文综述了茶叶及植物源样品中PAs检测的前处理方法和色谱-质谱检测技术的发展,并展望其发展趋势;总结了不同国家茶叶PAs污染水平,分析了茶叶中PAs种类含量的差异、各茶叶种类之间的PAs差异以及茶叶与其它食品或农产品中PAs差异,解析了茶叶中PAs对人体的健康风险。我国茶叶PAs污染水平监测与风险评估研究相关数据基本缺失,急需开展茶叶中PAs污染来源与风险评估研究。

关键词: 吡咯里西啶生物碱, 茶叶, 检测方法, 污染水平, 健康风险

Abstract: Abstract:Pyrrolizidine alkaloids (PAs) are secondary metabolites of plants, among which 1,2-unsaturated pyrrolizidine alkaloids and most pyrrolizidine alkaloid N-oxides (PANOs) have multiple toxic effects. PAs have been found widely in various kinds of tea samples, and have become one of the main contaminants hindering the export of tea in China. This study reviewed the development of pretreatment methods and chromatographic-mass spectrometry detection techniques for PAs in tea and plant-derived samples, and looked forward to their development trends. The present review summarized the levels of PAs pollution in tea from different countries in recent years, and profiled the differences of PAs contaminated levels among tea types, as well as between tea and other food or agricultural products. Health risk of PAs in tea was evaluated based on the study of PAs toxicity. The data related to PAs pollution levels and risk assessment of tea in China are basically missing, so it is urgent to trace the resource of PAs pollution and risk assessment of tea.

Key words: pyrrolizidine Alkaloids, tea, analytical methods, contaminated levels, health risks

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