食品科学 ›› 2010, Vol. 31 ›› Issue (11): 282-288.doi: 10.7506/spkx1002-6630-201011062

• 专题论述 • 上一篇    下一篇

麦角生物碱的研究进展

卢春霞,王洪新*   

  1. 食品科学与技术国家重点实验室,江南大学食品学院
  • 收稿日期:2009-10-28 修回日期:2010-01-20 出版日期:2010-06-01 发布日期:2010-12-29
  • 通讯作者: 王洪新 E-mail:whx1964@126.com
  • 基金资助:

    “十一五”国家科技支撑计划项目(2007BAK36B06)

Research Progress of Ergot Alkaloids

LU Chun-xia,WANG Hong-xin*   

  1. State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University,
    Wuxi 214122, China
  • Received:2009-10-28 Revised:2010-01-20 Online:2010-06-01 Published:2010-12-29
  • Contact: WANG Hong-xin E-mail:whx1964@126.com

摘要:

麦角生物碱是由麦角菌属(Claviceps)产生的生物碱毒素,易引起人和动物麦角中毒,同时也具有多种生物活性,主要用于治疗偏头疼、产后出血、乳腺病、帕金森病、脑血管系统等疾病。本文详细阐述了麦角碱的产生、理化性质、生物合成、危害、生物活性以及检测方法。

关键词: 麦角生物碱, 生物合成, 基因, 检测

Abstract:

Ergot alkaloids are mycotoxins, which are produced from fungi in the family of Clavicipitaceae. Toxicity of ergot alkaloids is an important issue to human and animals. However, ergot alkaloids exhibited a therapeutic effect on some forms of migraine, postpartum hemorrhages, mastopathy, Parkinson s disease, cerebrovascular insufficiency and venous insufficiency. This paper reviews the production of ergot alkaloids, physical and chemical properties, biosynthesis, hazards, biological activity, as well as the detection method.

Key words: ergot alkaloids, biosynthesis, gene, detection

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