食品科学 ›› 2010, Vol. 31 ›› Issue (21): 361-364.doi: 10.7506/spkx1002-6630-201021082

• 营养卫生 • 上一篇    下一篇

提取紫薯淀粉的副产物对SHR 血压的影响

胡志和1, 张然嬉1,冯永强2,朱利民2   

  1. 1.天津市食品生物技术重点实验室,天津商业大学生物技术与食品科学学院 2.天津海河乳业有限公司
  • 收稿日期:2010-06-27 出版日期:2010-11-15 发布日期:2010-12-29
  • 通讯作者: 胡志和 E-mail:huzhihe1008@yahoo.com.cn

Effect of Purple Potato Homogenate and Its Separated Fractions on Blood Pressure of SHR

HU Zhi-he1, ZHANG Ran-xi1, FENG Yong-qiang2, ZHU Li-min2   

  1. 1.Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of Commerce,
    Tianjin 300134, China ;2. Tianjin Haihe Dairy Co. Ltd., Tianjin 300402, China
  • Received:2010-06-27 Online:2010-11-15 Published:2010-12-29
  • Contact: HU Zhi-he E-mail:huzhihe1008@yahoo.com.cn

摘要:

以紫薯为原料,12 周龄雄性原发性高血压大鼠(SHR)和Wistar 大鼠为受试动物,研究紫薯全粉、滤渣、淀粉、水溶性提取物的降血压作用。上述分别以低、中、高3 个剂量(0.1、1、5g/ kg bw)灌胃SHR 大鼠和Wistar大鼠,观察对大鼠血压的影响。结果表明:在所选定的灌胃剂量范围内紫薯各成分对正常大鼠(Wistar 大鼠)血压无影响。除淀粉外,其他各成分对SHR 大鼠的血压均具有显著降低的作用,其中以水溶性提取物作用最为明显,灌胃后,低剂量组在1h 时达到最低值,下降了 20.83mmHg,中剂量组在2h 时达到最低值,下降了23.50mmHg,高剂量组在4h 时达到最低值,下降了24.48mmHg,然后血压开始慢慢回升,在8h 时基本恢复到灌胃前的水平。提取紫薯淀粉后的副产物均有明显降血压作用。

关键词: 紫薯, 高血压, 原发性高血压大鼠, 淀粉

Abstract:

Purple potato homogenate was filtrated through multiple layers of gauze, and both the filtrate and residue were harvested. After a period of time of sedimentation, the filtrate was separated into two layers, namely water-soluble upper layer and starch-rich lower layer. The effects of purple potato homogenate, its filtration residue and the water soluble and starch-rich factions of its filtrate on blood pressure of spontaneously hypertensive rats (SHR) was investigated by using 12-week-old male SHR and Wistar rats as the trial animals with different gavage administration doses (0.1, 1 g/kg bw and 5 g/kg bw). The results showed that none of the above four materials had an obvious effect on the blood pressure of normal Wister rats in the given dose range. Except the starch-rich fraction, all the others had a significant effect on decreasing blood pressure of SHR. The water-soluble fraction was the most effective antihyperglycemic factor with 20.83 mmHg drop at 1 hour after administration at 0.1 g/kg bw, 23.50 mmHg at 2 hours after administration at 1 g/kg bw, 24.48 mmHg at 4 hours after administration at 5 g/kg bw. These drops were followed by a slow rebound up to the pre-administration level at 8 hours. From these results, it can be concluded that all the byproducts of purple potato starch extraction have a notable antihyperglycemic effect.

Key words: purple potato, hypertension, spontaneously hypertensive rats (SHR), starch

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