食品科学 ›› 2011, Vol. 32 ›› Issue (15): 273-276.doi: 10.7506/spkx1002-6630-201115060

• 营养卫生 • 上一篇    下一篇

南极磷虾油改善大鼠学习记忆能力研究

刘 云,王亚恩,李立德,徐 恺,田 丹,姜国良*   

  1. 中国海洋大学海洋生命学院
  • 收稿日期:2018-04-20 修回日期:2018-04-20 出版日期:2011-08-15 发布日期:2011-07-26

Antarctic Krill Oil Improves Learning and Memory of Rats

LIU Yun,WANG Ya-en,LI Li-de,XU Kai,TIAN Dan,JIANG Guo-liang*   

  1. (College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China)
  • Received:2018-04-20 Revised:2018-04-20 Online:2011-08-15 Published:2011-07-26

摘要: 目的:观察南极磷虾油对Wistar大鼠学习记忆能力的影响。方法:采用Morris水迷宫法及Y-型迷宫刺激法观察,比较南极磷虾油和深海鱼油对大鼠学习记忆能力的作用。结果:Morris水迷宫实验显示南极磷虾油能够显著减少大鼠寻找平台潜伏期时间并且增加垮台次数和目标区域游泳时间所占比例(P<0.05或P<0.01);Y-型迷宫刺激实验表明南极磷虾油能够显著减少大鼠达标所需次数,显著提高48h后的实验正确率(P<0.05或P<0.01)。结论:南极磷虾油可显著改善大鼠学习记忆能力,且效果优于深海鱼油。

关键词: 南极磷虾油, 学习记忆, Morris水迷宫, Y-型迷宫刺激器, Wistar大鼠

Abstract: Objective: To observe the effect of Antarctic krill oil on the improvement of learning and memory of rats. Methods: The effect of Antarctic krill oil and deep sea fish oil on learning and memory of rats was evaluated by Morris-water maze and Y-shaped maze methods. Results: Antarctic krill oil could significantly reduce the latency of escaping onto the platform, and increase the frequency of crossing the platform and the proportion of swimming time of rats in the target area of Morris-water maze. Y-shaped maze results indicated that Antarctic krill oil could significantly reduce the number required for achieving the goal and improve the correct response rate after 48 h. Conclusion: Antarctic krill oil can improve learning and memory of rats and the effectiveness is better than that of deep sea fish oil.

Key words: Antarctic krill oil, learnimg and memory, Morris-water maze, Y-shaped maze, Wistar rats

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