关键词: 高通量, 生物信息学, 过敏组学, 食物过敏

Abstract: The study on allergens offers a foundation for preventing and treating food allergy, which is a serious health and safety issue all over the world. As the era of big data is coming, it is possible to study allergens by using high-throughput omics approaches, which facilitates the emergence and development of allergomics. Allergomics is a discipline that studies allergome-a collection of allergens with high throughput, wide coverage and excellent rapidity and sensitivity, which can provide the basis for personalized allergen avoidance and allergy immunotherapy. In the present review, the principle of allergomics and the current methods used in allergomics studies are summarized. In addition, the advantages and limitations of these approaches are discussed, and the future prospects of allergomics are proposed, which will provide guidance for the application and development of allergomics, especially in the field of food safety.

Key words: high-throughput, bioinformatics, allergomics, food allergy