食品科学 ›› 2023, Vol. 44 ›› Issue (15): 407-417.doi: 10.7506/spkx1002-6630-20220704-032

• 专题论述 • 上一篇    

碳水化合物食品血糖生成指数值体外、体内预测方法的研究进展

王怀槟,彭星光,刘宏生,余稳稳   

  1. (1.暨南大学食品科学与工程系,广东 广州 510632;2.华南理工大学食品科学与工程学院,广东 广州 510641)
  • 发布日期:2023-09-01
  • 基金资助:
    达能营养中心膳食营养研究与宣教基金项目(DIC2021-06)

Current Development of in Vitro and in Vivo Methods for Predicting Glycemic Indexes of Carbohydrate Foods

WANG Huaibin, PENG Xingguang, LIU Hongsheng, YU Wenwen   

  1. (1. Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China; 2. School of Food Science and Engineering, South China University of Technology, Guangzhou 510641, China)
  • Published:2023-09-01

摘要: 血糖生成指数(glycemic index,GI)是评估碳水化合物食品餐后血糖反应的关键指标。低GI饮食不仅能帮助控制食欲和延缓饥饿,有助于控制体质量,更能改善糖尿病人的葡萄糖和脂质水平。开发低GI食品已成为国内外食品科学研究的热点和焦点。当前,国际标准组织(International Organization for Standardization,ISO)出台的人体规范测试ISO 26642:2010是各国家/地区测试食品GI值的“金标准”。但人体测试存在个体差异对实验结果影响明显、费用昂贵、耗时长且受伦理道德约束等缺点,不适合高通量食品GI值测试。为此研究者们又陆续开发了各种体外模型来预测食品GI值。本文重点讨论了当前可预测食品GI值的各种体外、体内方法,分析比较其优缺点及今后发展的着力点,旨在为低GI食品研发与推广提供新的思路和具有参考意义的检测工具。

关键词: 血糖生成指数;碳水化合物;淀粉;检测;体外消化

Abstract: Glycemic index (GI) is a key indicator for evaluating the postprandial glycemic response to carbohydrate foods. A low GI diet can not only help to control appetite and delay hunger, but also benefit weight control and improve glucose and lipid levels in diabetic patients. The development of low GI foods has thus become a hotspot in current food research. At present, the international standard ISO 26642:2010, issued by the International Standards Organization (ISO), is the gold standard for measuring the GI values of foods using human subjects around the world. However, human testing has some disadvantages, such as individual differences may lead to significantly different results, even for the same foods, and it is costly and time consuming, and should be ethical, and it is unsuitable for high-throughput testing of food GI values. For this reason, researchers have successively developed various in vitro models to predict food GI values. This article focuses on reviewing the current in vitro and in vivo methods for predicting the GI values of foods, with a particular focus on their advantages and disadvantages, as well as their future developments. The current paper is aimed to provide new ideas for the development and promotion of low GI foods.

Key words: glycemic index; carbohydrate; starch; assay; in vitro digestion

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