口服沙棘油对游泳小鼠肝、心、脑自由基代谢影响的实验研究

摘要/Abstract

摘要： 本实验以雄性ICR(SwissHauschka)小鼠为实验对象,将其随机分为安静对照组(A)、安静沙棘组(B)、训练即刻组(C)、训练即刻沙棘组(D)、训练恢复24小时组(E)、训练恢复24小时沙棘组(F)。经过6周游泳耐力训练后进行一次力竭性游泳,观察了各组小鼠肝脏、心肌及脑组织超氧化物歧化酶(SOD)、丙二醛(MDA)等指标。结果表明:以上各组除E与F间无显著差异外(P>0.05),肝脏SOD其余各组间均有显著差异(P<0.05),与A、C、E组相比,B、D、F组SOD活性分别升高7.39%、13.1%及-0.716%;心肌SOD除A与B与F间无显著差异外(P>0.05),其余各组间均有显著差异(P<0.05),与A、C、E组相比,B、D、F组SOD活性分别升高-0.612%、4.76%及26.0%;脑SOD除A与B,E与F,A与C间无显著差异外(P>0.05),其余各组间均有显著差异(P<0.05),与A、C、E组相比,B、D、F组SOD活性分别升高-1.95%、3.88%及0.992%。对MDA而言,肝脏除C与D、E与F间无显著差异外(P>0.05),其余各组均有显著差异(P<0.05);与A、C、E组相比,B、D、F组MDA含量分别降低25.6%、6.06%及3.73%;心肌变化与肝脏相似,与A、C、E组相比,B、D、F组MDA含量分别降低34.1%、5.05%及-0.285%;脑中各组间变化不大,与A、C、E组相比,B、D、F组MDA含量分别降低5.11%、-2.29%及0.631%。本实验的研究结果表明,沙棘油

关键词: , ICR小鼠, 沙棘油, 游泳训练, 超氧化物歧化酶, 丙二醛

Abstract: 70 male ICR mice were randomly divided into six groups:sedentary control group(A),sedentary+oil of Hipprphae rhamnoides(OHR) group(B),immediately exhaustive exercise in control group(C),immediately exhaustive exercise in OHR supplementation group(D),24h recovery exhaustive exercise in control group(E),24 h recovery exhaustive exercise in OHR supplementation group(F).After 6-week swimming program with gradually increasing intensity,these mice carried out an exhaustive swimming before sacrifice.SOD and MDA in liver,myocardium and brain were assayed.The results indicated.1) SOD showed difference among these groups except between E and F in liver except between A and B,D and F in myocardium,except between A and B ,E and F,A and C in brain. when Comparing with A,C and E, SOD activity in B, D and F increased 7.39%,13.1% and -0.716% respectively in liver 0.612%,4.76% and 26.0% respectively in myocardium,and -1.95%,3.88% and 0.992%.2) The concentration of MDA showed significant difference among above groups except between C and D and E and F in liver and myocardium;-no significant difference among above groups in brain.Comparing with A,C and E,MDA content in B,D and F decreased 25.6%,6.06% and 3.37%,respectively in liver,34.1%,5.05% and 0.285% respectively in myocardium,5.11%,-2.29% and 0.631% respectively in brain.So the conclusion luas:OHR supplementation could increase swimming performance significantly,enhance antioxidative status liver,myocardium and brain.

Key words: ICR mice Oil of Hippophae rhamnoides(OHR) Swimming training SOD MDA

刘小杰, 何国庆, 熊正英. 口服沙棘油对游泳小鼠肝、心、脑自由基代谢影响的实验研究[J]. 食品科学, 2001, 22(10): 71-74.

LIU Xiao-Jie, He-Guo-Qing, Xiong-Zheng-Ying. Oral OHR Study on SOD MDA Assay in ICR Mice Liver Mgcocardium and Brain affer Exhaustive swimming[J]. FOOD SCIENCE, 2001, 22(10): 71-74.

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口服沙棘油对游泳小鼠肝、心、脑自由基代谢影响的实验研究

Oral OHR Study on SOD MDA Assay in ICR Mice Liver Mgcocardium and Brain affer Exhaustive swimming

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