食品科学 ›› 2001, Vol. 22 ›› Issue (11): 56-57.

• 营养卫生 • 上一篇    下一篇

茶多酚延缓衰老作用的分子生物机理研究——对小鼠肝DNA甲基化酶活力的影响

 陈比特,  林一萍,  陈玉春   

  1. 福建省中医药研究院
  • 出版日期:2001-11-15 发布日期:2012-02-14

Effect Study of TP on DNA Methylating Enzyne Vitality in Mouse Liver

 CHEN  Bi-Te,   Lin-Yi-Ping,   Chen-Yu-Chun   

  • Online:2001-11-15 Published:2012-02-14

摘要: 采用一定浓度的茶多酚(Teapolyphenols,TP)和人参汤剂处理老年和成年小鼠;并用3H-甲基掺入法测定了小鼠肝DNA甲基化酶的活力。结果证明TP和0.2%的人参汤剂能明显提高老年小鼠肝细胞DNA甲基化酶的活力,具有延缓衰老的作用,为从分子生物的角度探讨TP延缓衰老的机理提供客观依据。

关键词: DNA甲基化酶, 肝细胞, 茶多酚, 人参, 延缓衰老

Abstract: The Tea polyphenols(TP) and Ginseng decocum were given to the senile mice and the DNA methylating enzyme vitality tests in the liver of Grown mice and senile mice were assayed with the method of3H- methy1 incorporation,The results showed that the TP and Ginseng decoctum could obviously enhance the DNA methylating enzyme vitality in the live cell in senile mice,which showed the effect of anti- senility.It provided the objective dvidence for studying the mechanism of IP for anti- senility from the viewpoint of molecular biology.

Key words: DNA methylating enzyme Live cell Polyphenols Ginseng Anti- senility