食品科学 ›› 2006, Vol. 27 ›› Issue (10): 521-524.

• 营养卫生 • 上一篇    下一篇

两种市售补钙制剂对生长期大鼠生物利用率的研究

 赵晓红,  米生权,  刘岩   

  1. 北京联合大学应用文理学院
  • 出版日期:2006-10-15 发布日期:2011-11-16

Bioavailability Study of Two Marketing Calcium Supplements on Growing Rat

 ZHAO  Xiao-Hong,   Mi-Sheng-Quan,   Liu-Yan   

  1. College of Applied Arts and Science, Beijing Union University, Beijing 100083, China
  • Online:2006-10-15 Published:2011-11-16

摘要: 市售补钙制剂种类繁多,良萎不齐,各种评价方法评价结果不尽一致,本文采用该吸收平台效应下剂量为实验剂量,利用表观吸收率等指标有效检验了两种市售复合补钙制剂。本文以生长期Wister大鼠为模型,用原子吸收测量了钙平衡后钙及其他元素的吸收率,并测量了股骨骨密度。结果显示在相同钙摄入量下,碳酸钙制剂吸收率低于氨基酸螯合钙(p<0.05),Zn、Mg、Pb的吸收量及吸收率均高于碳酸钙组(p<0.01或p<0.05),骨密度两组差异没有统计学意义。由此可见复合氨基酸螯合钙制剂钙生物利用率优于复合碳酸钙制剂,但其重金属和微量元素也有较高的吸收率。

关键词: 补钙制剂, 生物利用率, 吸收率, 骨密度

Abstract:  Consumers were confused by the numbers and types of different preparations of calcium supplements as more and more subgroup of the population are recommended to increase their daily calcium intake. In this study, a dose under threshold of calcium intake was conducted to compared the bioavailability of two marketing calcium supplements. Ca, Zn, Mg and Pb were measured by FAAS or GFAAS, after a long term calcium balance on growing Wister female rats, bone density of right thighbone were measured. The results showed that the apparent absorbability of the compound calcium carbonate was lower than the compound calcium amino acid chelate(p<0.05),but the absorbabilities of Zn, Mg, Pb were higher (p<0.01 or p<0.05). And the bone density of right thighbone were not significant (p>0.05) between two calcium supplements. It suggest that the bioavailability of calcium from calcium amino acid chelate was superior to one of the calcium carbonate, but absorbability of the heavy metals should be concerned at the same time.

Key words:  , calcium supplement; bioavailability; absorbability; bone density;