关键词: 肠黏膜屏障, 肠黏膜免疫, SIgA, 免疫细胞, 肠道菌群, 益生元

Abstract: Intestinal mucosal barrier play an important role in preventing the diseases caused by direct contact of bacteria,food antigen,enzyme,chemical drugs with mucosal surface. The intestinal mucosal immunity barrier which is beneficial for body health has arisen more and more people’s concerns. This system not only has run-of-mill barrier effect,but also takes part in the process of humoral immunity and cellular immunity,which plays an important role in the regulation of microenvironment of gut. With the thorough research,the new strategies for restoring and maintaining human health might be provided. The paper described the regulatory mechanism of intestinal mucosal immunity,the effects of the intestinal microflora and nutrients on the function of intestinal mucosal barrier and the harm of intestinal barrier damage to body health.

Key words:  , intestinal mucosal barrier； intestinal mucosal immunity； SIgA； immune cell； intestinal microflora； prebiotics；