天麻多糖PGEB-3-H对大鼠肠道内短链脂肪酸的影响

doi:10.7506/spkx1002-6630-201111059

食品科学 ›› 2011, Vol. 32 ›› Issue (11): 284-287.doi: 10.7506/spkx1002-6630-201111059

天麻多糖PGEB-3-H对大鼠肠道内短链脂肪酸的影响

令博，赵国华，明建

1.西南大学食品科学学院 2.重庆市特色食品工程技术研究中心

出版日期:2011-06-15 发布日期:2011-05-13
基金资助:
中央高校基本科研业务费专项资金资助项目(XDJK2009C044)；西南大学博士基金项目(SWU109005)

Effect of Polysaccharide PGEB-3-H from Gastrodia elata Blume on Short Chain Fatty Acids in the Intestinal Tract of Rats

LING Bo1，ZHAO Guo-hua1,2， MING Jian1,2,*

1. College of Food Science, Southwest University, Chongqing 400715, China； 2. Chongqing Special Food Programme and Technology Research Center, Chongqing 400715, China

Online:2011-06-15 Published:2011-05-13

摘要/Abstract

摘要： 研究天麻多糖PGEB-3-H对大鼠肠道内短链脂肪酸(SCFA)的影响。以SD大鼠为实验模型，进行分组喂养，分别以高剂量(400mg/(kg ·d))、中剂量(200mg/(kg ·d))、低剂量(100mg/(kg ·d))的天麻多糖PGEB-3-H灌胃，为期4周，定期收集大鼠粪便样。粪便处理后通过气相色谱法测定其中SCFA的含量。结果表明：天麻多糖PGEB-3-H对大鼠肠道内乙酸、丙酸、丁酸、异丁酸、戊酸和己酸的产生有较大影响，而对异戊酸和庚酸作用不明显；不同灌胃剂量对大鼠肠道SCFA的影响也有较大差异，以中剂量和低剂量多糖对SCFA的产生影响明显，各剂量组大鼠肠道内SCFA含量在7～14d时最多。

关键词: 天麻, 多糖, 短链脂肪酸, 大鼠

Abstract: In this paper, the effect of polysaccharide PGEB-3-H on short chain fatty acids in the intestinal tract of rats was investigated. SD rats were used as experimental models and administered with PGEB-3-H at high, medium and low doses (400, 200 mg/(kg ·d) and 100 mg/(kg ·d) for 4 consecutive weeks. The stool samples of rats were collected at the designed time points. The short chain fatty acids in the intestinal tract of rats were analyzed by gas chromatography. Results indicated that polysaccharide PGEB-3-H had an obvious effect on the production of ethanoic acid, propionic acid, butyric acid, isobutyric acid, valeric acid and caproic acid; in contrast, it did not reveal an obvious effect on the production of isovaleric acid and heptanoic acid. Meanwhile, different administration doses of PGEB-3-H also revealed different effects on short chain fatty acids. An obvious effect on the production of short chain fatty acids was observed in the medium and low dose groups of PGEB-3-H. The highest level of short chain fatty acid production in the intestinal tract of rats was observed in the period of 7－14 d after the administration of PGEB-3-H.

Key words: Gastrodia elata Blume, polysaccharide, short chain fatty acid, rat

中图分类号:

R972.6

令博，赵国华，明建. 天麻多糖PGEB-3-H对大鼠肠道内短链脂肪酸的影响[J]. 食品科学, 2011, 32(11): 284-287.

LING Bo，ZHAO Guo-hua， MING Jian. Effect of Polysaccharide PGEB-3-H from Gastrodia elata Blume on Short Chain Fatty Acids in the Intestinal Tract of Rats[J]. FOOD SCIENCE, 2011, 32(11): 284-287.

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天麻多糖PGEB-3-H对大鼠肠道内短链脂肪酸的影响

Effect of Polysaccharide PGEB-3-H from Gastrodia elata Blume on Short Chain Fatty Acids in the Intestinal Tract of Rats

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