[1] BENNETT J W, KLICH M. Mycotoxins [J]. Clinical Microbiology Reviews, 2003, 16(3):497-516.[2] GOSWAMI RS, XU J R, TRAIL F, Hilburn K, Kistler HC, et al. Genomic analysis of host-pathogen interaction between Fusarium graminearum and wheat during early stages of disease development [J]. Microbiology-sgm, 2006, 152:1877–1890.[3] ERIKSEN G S,ALEXANDER J.Fusarium toxins in cereals a risk assessment [J].Nordic Council of Ministers,Terma Nord,1998, 508:7-44.[4] ROTTER B A, PRELUSKY D B, PESTKA J J, et al. Toxicology of deoxynivalenol(vomitoxin)[J]. Journal of Toxicol Environmental Health, 1996, 48(1):1–34.[5] SCHLATTER J. Toxicity data relevant for hazard characterization [J]. Toxicology Letters, 2004, 153: 83-83.[6] PESTKA J J, SMOLINSKI A T. Deoxynivalenol: toxicology and potential effects on humans [J]. Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2005, 8(1):39-69.[7] EFSA. Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to deoxynivalenol (DON) as undesirable substance in animal feed [J]. EFSA, 2004, 73:1–41.[8] JAMES J, PESTKA, ZHOU Hui-Ren. et al. Cellular and molecular mechanisms for immune modulationby deoxynivalenol and other trichothecenes: unraveling a paradox[J]. Toxicology Letters, 2004, 153:61-73. [9] VESONDER R F, CIEGLER A, JENSEN A H, Isolation of the emetic principle from Fusarium-Infected corn [J].Applied microbiology, 1973, 26(6):1008-1010.[10] JAMES J, PESTKA. Deoxynivalenol: Toxicity, mechanisms and animal health risks [J]. Animal Feed Science and Technology, 2007, 137: 283-298.[11] JEANETTE K S, NIELSEN, ANNA C, et al. Deoxynivalenol transport across the human placental barrier [J].Food and Chemical Toxicology. 2011, 49:2046-2052.[12] MIROCHA C J, PATHRE S V, SCHAUERHAMER B, et al. Natural occurrence of Fusarium toxins in feedstuff [J]. Applied Environmental Microbiology, 1976, 32: 553-556.[13] WOLF C E,BULLERMAN L B. Heat and pH alter the concentration of deoxynivalenol in an aqueous environment [J].Food Product, 1998, 61(3): 365-367[14] JO INT FAO. WHO Expert Committee on Food Additives ( JECFA). Safety evaluation of certain mycotoxins in food. Deoxyni2valenol toxin. AO Food and Nutrition Paper 74 [EB /OL ]. ( 2001 ). http: / /www. inchem. org/documents/ jecfa / jecmono / v47 je01. htm.[15] WHO Technical Report Series 906 [ EB /OL ]. Joint FAO,WHO Expert Committee on Food Additives. 56 th Report. Geneva. Switzerland. [ 1996 - 06 - 19 ]. http: / /www. foodmate. net/ standard /gb /gb16329. htm.[16] TANAKA K, SAGO Y, ZHENG Ya-zhi, et al. Mycotoxins in rice [J].International Journal of Food Microbiology, 2007, 119(2): 59-66.[17] PESTKA J J, SMOLINSKI A T. Deoxynivalenol: toxicology and potential effects on humans [J]. Journal of Toxicology and Environmental Health Part B, Critical Reviews, 2005, 8(1): 39-69.[18] 中华人民共和国卫生部、中国国家标准化管理委员会.GB2761 - 2005食品中真菌毒素限量[S].中国国家标准出版社,2005.[19] 中华人民共和国卫生部、中国国家标准化管理委员会.GB13078.3 – 2007配合饲料中脱氧雪腐镰刀菌烯醇的允许量[S].中国国家标准出版社,2007.[20] WAGEHA A, AWAD, GHAREEB K, et al. Decontamination and detoxification strategies for the Fusarium mycotoxin deoxynivalenol in animal feed and the effectiveness of microbial biodegradation [J]. Food Additives and Contaminants, 2010, 27(4): 510-520.[21] SHIMA J,TAKASE S,TAKAHASHI Y ,et al. Novel detoxification of the trichothecene mycotoxin deoxynivalenol by a soil bacterium isolated by enrichment culture [J]. Applied Environmental Microbiology, 1997,63(10) :3825-3830.[22] V?LKL A,VOGLER B, SCHOLLENBERGER M, et al. Microbial detoxification of mycotoxin deoxynivalenol [J]. Journal of Basic Microbiology, 2004, 44(2) : 147-156.[23] HE Ping, YOUNG L G, FORSBERG C. Microbial transformation of deoxynivalenol(vomitoxin) [J]. Applied Environmental Microbiology, 1992, 58(12) :3857-3863.[24] ERIKSEN G S, PETTERSSON H, LUNDH T. Comparative cytotoxicity of deoxynivalenol, nivalenol, their acetylated derivatives and de-epoxy metabolites [J]. Food and Chemical Toxicology, 2004, 42: 619-624.[25] BINDER E M, BINDER J, ELLEND N, et al. Microbiological degradation of deoxynivalenol and 3-acetyl-deoxynivalenol Mycotoxins and Phycotoxins: Developments in Chemistry [J]. Toxicology and Food Safety, 1998, 279-285.[26] AWAD W A, B?HM J, RAZZAZI-FAZELI E, et al. Effects of deoxynivalenol on general performance and electrophysiological properties of intestinal mucosa of broiler chickens [J]. Poultry Science, 2004, 83: 1964-1972.[27] AWAD W A, RAZZAZI-FAZELI E, B?HM J, et al. Effect of addition of a probiotic microorganism to broiler diets contaminated with deoxynivalenol on performance and histological alterations of intestinal villi of broiler chickens [J]. Poultry Science, 2006, 85: 974-979.[28] FUCHS E, BINDER E M, HEIDLER D,et al. Structural characterization of metabolites after the microbial degradation of type A trichothecenes by the bacterial strain BBSH 797 [J]. Food additives and contaminants, 2002, 19(4) :379-386.[29] HE Jian-wei, ZHOU Ting, CHRISTOPHER Young J, et al. Chemical and biological transformations for detoxification of trichothecene mycotoxins in human and animal food chains: a review [J].Trends in Food Science & Techonlogy , 2010,(20) :67-76.[30] HOCHSTEINER, W, SCHUH M, LUGER K, et al. Influence of mycotoxins contaminated feed blood parameters and milk production [J]. Berliner und Munchener Tierarztliche Wochenschrift, 2000, 113: 14-21.[31] PLANK B, SCHUH M, BINDER E M, et al. Investigations on the effect of two feed additives, Biomin (R) BBSH 797 and Mycofix Plus (R) 3.E, as detoxificants of DON contaminated feed of piglets [J]. Wiener tierarztliche monatsschrift, 2009, 96(3-4): 55-71.[32] YU Hai, ZHOU Ting, GONG Jian-hua.,et al. Isolation of deoxynivalenol-transforming bacteria from the chicken intestines using the approach of PCR-DGGE guided microbial selection [J]. BMC Microbiology, 2010, 10:182-186[33] GUAN Shu, HE Jian-wei, J CHRISTOPHER Y,et al. Transformation of trichothecene mycotoxins by microorganisms from fish gigesta [J]. Aquaculture, 2009, 290:290-295.[34] LI XZ, ZHU C, DE LANG C F M, et al. Efficacy of detoxification of deoxynivalenol-contaminated corn by Bacillus sp. LS100 in reducing the adverse effects of the mycotoxin on swine growth performance [J]. Food Additives & Contaminants: Part A, 2011, 28(27): 894-901.[35] HE Cheng-hua, FAN Yan-hong, LIU Guo-fang, et al. Isolation and Identification of a Strain of Aspergillus Tubingensis With Deoxynivalenol Biotransformation Capability [J]. International Journal of Molecular Sciences, 2008, 9: 2366-2375.[36] 何成华.脱氧雪腐镰刀菌烯醇毒性和生物转化的研究[D].南京农业大学,2007.[37] KIMURA M, KANEKO I, KOMIYAMA M, et al. Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins [J]. Journal of Biological Chemistry, 2007, 273: 1654-1661.[38] POPPENBERGER B, BERTHILLEr F, LUCYSHYN D, et al. Detoxification of the Fusarium mycotoxin deoxynivalenol by a UDP-glucosyltransferase from Arabidopsis thaliana [J]. Journal of Biological Chemistry, 2003, 278: 47905-47914.[39] WU Xia-nai, MURPHY P, CUNNICK J, et al. Synthesis and characterization of deoxynivalenol glucuronide: its comparative immunotoxicity with deoxynivalenol [J]. Food and Chemical Toxicology, 2007, 45: 1846-1855. [40] ADAM G, MITTERBAUEr R, RADITSCHNIG A, et al. Molecular Mechanisms of Deoxynivalenol Resistance in the Yeast Saccharomyces Cerevisiae [J]. Mycotoxin Research, 2001, 17(9): 19-23.[41] MA Lu-lin, SHANG Yi, CAO Ai-zhong, et al. Molecular cloning and characterization of an up-regulated UDP-glucosyltransferase gene induced by DON from Triticum aestivum L. cv. Wangshuibai [J]. Molecular Biology reports, 2010, 37(2):785-795.[42] KHATIBI P, MONTANTI J, NGHIEM N, et al. Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley-derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases [J]. Biotechnology for Biofuels, 2011, 4: 26-38.[43] IKUNAGA Y , SATO I, GROND S, et al. Nocardioides sp. strain WSN05-2, isolated from a wheat field, degrades deoxynivalenol,producing the novel intermediate 3-epi-deoxynivalenol [J]. Applied Microbiology and Biotechnology, 2011, 89(2): 419–427.[44] NIDERKORN V, BOUDRA H, MORGAVI D P. Binding of Fusarium mycotoxins by fermentative bacteria in vitro [J].Journal of applied microbiology, 2006, 101(4): 849-856.[45] GARDA-BUFFON J, BADIALE-FURLONG E. Kinetics of deoxynivalenol degradation by Aspergillus oryzae and Rhizopus oryzae in submerged fermentation [J]. Journal of the Brazilian Chemical Society, 2010, 21(4): 710-714.[46] STYRIAK I, CONKOVA E, KMEC V , et al. The use of yeast for microbial degradation of some selected mycotoxins [J]. Mycotoxin Research, 2011, 17(1): 24-27.[47] HALADY SHETTY P, JESPESEN L. Saccharomyces Cerevisiae and lactic acid bacteria as potential mycotoxin decontaminaying agents [J]. Trends in Food Science & Technology, 2006, 17: 48-55.[48] CHENG Bo-cai, WAN Cui-xiang, YANG Shi-liang, et al. Detoxification of deoxynivalenol by Bacillus strains [J]. Journal of Food Safety, 2010, 30: 599-614. |