食品科学 ›› 2012, Vol. 33 ›› Issue (1): 290-293.

• 专题论述 • 上一篇    下一篇

一种新型补充矿物元素的载体——脱铁铁蛋白的研究进展

王 震,冷小京*   

  1. 中国农业大学食品科学与营养工程学院
  • 收稿日期:2011-01-17 修回日期:2011-12-27 出版日期:2012-01-15 发布日期:2012-01-12
  • 通讯作者: 冷小京 E-mail:xiaojing.leng@gmail.com
  • 基金资助:

    “十二五”国家科技支撑计划项目

Ferritin: A New Mineral Carrier for Supplement

,Zhen WANG   

  • Received:2011-01-17 Revised:2011-12-27 Online:2012-01-15 Published:2012-01-12

摘要: 铁蛋白(ferritin)经脱铁处理后,内部空腔可装载多种矿物元素。鉴于这种蛋白可经胞饮作用,完整地被小肠上皮细胞吸收,因此有望作为新型矿物元素载体而发展。脱铁铁蛋白(apoferritin)的脱铁及矿物元素的装载过程可利用透射电镜(TEM)、能谱分析(EDS)、X射线粉末衍射(X-Ray)、质谱(MS)、核磁共振(NMR)、动态光散射(DLS)、紫外分光光度法(UV)等技术研究分析。本文综述了目前国内外利用铁蛋白装载矿物元素的成果及其在营养方面的应用。

关键词: 铁蛋白, 脱铁铁蛋白, 矿物元素, 载体

Abstract: The cavity of apoferritin can be used to transport various minerals. Since this protein can be absorbed by intestinal epithelial cells via entocytosis pathways, it becomes a new promising type of mineral nanocarrier. The process of deferrization for ferritin and mineral loading has been studied by transmission electron microscope (TEM), energy dispersive X-ray spectroscopy (EDS), X-ray powder diffraction (X-Ray), mass spectroscopy (MS), nuclear magnetic resonance (NMR), dynamic light scattering (DLS) and ultraviolet spectroscopy (UV), respectively. Recents applications of apoferritin carriers in the field of nutrition are summarized in this paper.

Key words: ferritin, apoferritin, mineral, carrier

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