关键词: 植物多糖, 抗肿瘤, 作用机制

Abstract: As a class of natural products with many biological activities, plant polysaccharides have become a research hotspot in the field of anti-tumor functional foods because of their advantages of high efficiency and low toxicity. Clinical anti-tumor trials have demons plant polysaccharides can alleviate immunosuppression, enhance immune response, and inhibit the growth, invasion and metastasis of tumors.?In this review, the anti-tumor plant polysaccharides that have been reported over the decade are summarized. The anti-tumor mechanisms of plant polysaccharides are elucidated from four perspectives: regulation of tumor microenvironment, targeted cancer cell therapy, iron metabolism and erythrocyte immunity. Finally, the structure-activity relationship of anti-tumor plant polysaccharides is also discussed, and future research directions are presented in order to promote in-depth studies of plant polysaccharides and provide a theoretical basis for the research and development of anti-cancer foods.

Key words: plant polysaccharides, antitumor, mechanism