FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (17): 392-396.doi: 10.7506/spkx1002-6630-201017088

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Research Progress in Metallothionein

LI Jian-rong1,XUAN Wei1,LI Xue-peng1,XIONG Chun-hua1,WANG Xi-chang2   

  1. 1. Food Safety Key Laboratory of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University,
    Hangzhou 310035, China;2. College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
  • Received:2010-01-19 Revised:2010-06-29 Online:2010-09-15 Published:2010-12-29
  • Contact: LI Jian-rong E-mail:lijianrong@zjgsu.edu.cn

Abstract:

Metallothionein (MT) is a cysteine-rich, highly conserved, low molecular and heavy metal-binding protein, which plays important roles in modulating concentrations of trace elements and detoxification of heavy metals. In addition, MT is also involved in the regulation of hormonal and cell metabolism, the control of cell differentiation and proliferation, UV reaction and the scavenging of free radicals. In this paper, current research progress in the properties, physiological functions, extraction and purification technologies and detection strategies of MT have been reviewed and application prospects have been proposed, which will provide theoretical references and a basis for its future development and applications.

Key words: metallothionein, physico-chemical characteristics, physiological function, heavy metal

CLC Number: