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Effects of Glycoprotein and Glycopeptides from Jellyfish on Immune Function of Mice in vitro

REN Guo-yan,LIU Zhi-long,GUO Jin-ying,FAN Jin-ling,LIANG Wang-chun,SHAO Zheng,KANG Huai-bin   

  1. College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471003, China
  • Online:2013-09-15 Published:2013-09-27
  • Contact: REN Guo-yan

Abstract:

The immunoregulatory activity of glycoprotein and glycopeptides from jellyfish was explored through cell
proliferation and cell transformation of mouse spleen lymphocytes and comparatively evaluated under various cultivation
times and concentrations. Jellyfish glycoprotein and glycopeptides revealed significant increase in the proliferation and
transformation of spleen lymphocytes in a dose-dependent manner. The results demonstrated that glycopeptides had
better immunoregulatory activity in vitro when spleen lymphocytes were cultivated for 60 hours and the concentration of
glycopeptides was 50 μg/mL.

Key words: jellyfish, glycoprotein, glycopeptides, immunomodulation in vitro

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