FOOD SCIENCE ›› 2017, Vol. 38 ›› Issue (9): 239-247.doi: 10.7506/spkx1002-6630-201709039

• Reviews • Previous Articles     Next Articles

Progress in Research on Natural Products in MicroRNA Regulation for Metabolic Syndrome Improvement

GUO Qin, BAI Jie, HE Yuxuan, TANG Chuanhui, CAO Qingguo, DONG Ying   

  1. 1. School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China; 2. Institute of Biological Engineering, Jiangsu Polytechnic College of Agriculture and Forestry, Jurong 212000, China
  • Online:2017-05-15 Published:2017-05-22

Abstract: The metabolic syndrome has become a global health problem. microRNA (miRNA), a short single-stranded endogenously expressed RNA (approximately 22 nt), regulates gene expression at the post-transcriptional level. A lot of researches have shown that miRNA plays an important role in metabolic syndromes. Additionally, natural products which can be used as both food and medicine can modulate the activities and functions of miRNA to improve glucose and lipid metabolism disorders. Recent evidence described in this review highlights the significant role of miRNA in metabolic syndromes and how dietary factors may influence metabolic syndromes by modulating the activities and functions of miRNA.

Key words: metabolic syndrome, microRNA (miRNA), natural products

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