Experimental Study of Soybean Isoflavones on Osteoporosis in Ovariectomized Rats

Abstract

Abstract: Osteoporosis mode was established through ovary resection of female rats,to investigate the preventive effect of soybean isoflavones(SIF)on osteroporosis of ovariectomized rats.The results showed that:SIF could significantly increase bone mineral density(BMD),improve the uterus index and the levels of estradiol(E2)in serum and at the same time reduce the AKP activity.SIF could efficiently prevent osteoporosis by reducing bone turnover rate and increasing BMP.

Key words: osteoporosis, soybean isoflavones, bone mineral density, estradiol, uterus index

WANG Yuan-Jin, XU Jin-Lin, ZHANG Jie, BAI Jiu, ZHAO Xian-Pu. Experimental Study of Soybean Isoflavones on Osteoporosis in Ovariectomized Rats[J]. FOOD SCIENCE, 2003, 24(2): 120-122.

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Experimental Study of Soybean Isoflavones on Osteoporosis in Ovariectomized Rats

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