Abstract: Objective: Antioxidation activities of vinegar in ageing-accelerating model mice were studied in this paper. Methods: Hengshun vinegar were concentrated to 13 of initial volume, and neutralized to pH6～7 or so. Amount of total phenolic compounds and total flavones in vinegar were determined. Mice (2 months age) were divided into five groups: ageing accelerating model and young control group, while the control group was gavage instilled normal saline. Vinegar groups were instilled 1.2, 0.6, 0.3gkg•d for 35 days respectively. MDA, SOD and GSH-Px of mice plasm were measured and liver index and spleen index were determined. Results: Hengshun vinegar (1.2gkg•d) could reduce the level of MDA, and increase the activities of SOD and GSH-Px. Hengshun vinegar may inhibit the reduction of liver index and spleen index. Hengshun aromatic vinegar (0.6gkg• d) might inhibit the reduction of GSH-PxLPO ratio caused by instilling D-galactose. Conclusion : Hengshun vinegar has shown antioxidation activities.

Key words: vinegar, antioxidation activity, mice, D-galactose