FOOD SCIENCE ›› 2008, Vol. 29 ›› Issue (10): 546-548.

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Study on Immune Activity of Radix Cynanchi Bungei Polysaccharides

 GAO  Li-Jun, WANG  Jian-Hua, CUI  Jian-Hua, WANG  Han-Zhong   

  1. 1.Department of Biological Sciences,Taishan Medical University,Taian 271016,China; 2.College of Agronomy,Shandong Agricultural University,Taian 271018,China; 3.School of Chemistry and Chemical Engineering,Taishan Medical University,Taian 271016,China
  • Online:2008-10-15 Published:2011-12-08

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Abstract: Objective:To study the effects of Radix Cynanchi Bungei polysaccharides (RCBPs) on transformation of T lymphocytes of rabbit phtohemagg luti and immune function in mice. Methods: Three doses of RCBPs (2,4 and 6 g/L) were respectively put into bottle with Pgytohemagg lutinin (PHA) and rabbit blood. The effect of RCBPs on immunity in vitro was studied by observing transformation of T lymphocytes; The dosages of RCBPs (150,100,50 mg/kg·d) were given to mice orally for seven days.The effects on immune function in the mice were investigated. Results: Three doses of RCBPs can significantly promote (p<0.01) the ability of rabbit T lymphocytes. The RCBPs can improve the Thymus and spleen indexes,the celiac macrophage ability of engulfing CRBC,the delayed type hypersensitivity ability and the macrophage-engulfing carbon granula ability. Conclusion: The RCBPs has certain activity of immune regulation.

Key words: Radix Cynanchi bungei, polysaccharides, immune activity