FOOD SCIENCE ›› 2012, Vol. 33 ›› Issue (13): 259-262.doi: 10.7506/spkx1002-6630-201213055

• Nutrition & Hygiene • Previous Articles     Next Articles

Short-Term Intervention of Lycium barbarum Polysaccharide on Type 2 Diabetes

CAIHui-zhen,LIUFu-kang,LUHui-xia,GUOFei,HULi-jie,HANChao,SUNGui-ju   

  1. (1. Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, College of Public Health, Southeast University, Nanjing 210009, China;2. College of Public Health, Ningxia Medicine University, Yinchuan 750004, China;3. Zhongda Hospital Affiliated, Southeast University, Nanjing 210009, China;4. Nanjing Jiangpu People , s Hospital, Nanjing 211800, China; 5. Sonergy Laboratories Shanghai Co. Ltd., Shanghai 200120, China)
  • Online:2012-07-15 Published:2012-07-27

Abstract: Objective: To study the effect of Lycium barbarum polysaccharide (LBP) on hypoglycemic activity and cytokine in type 2 diabetic patients. Methods: The 1:1 matching method was used to select subjects according to their age (difference no more than 5 years old), duration of diabetes (difference no more than 5 years) and drug type and doses. LBP or placebo was provided by 300 mg/d for 3 consecutive months. Results: Fasting serum glucose and TNF-α had a significant difference between two groups after administration for 3 months. However, no significant difference was observed in leptin, interleukin 6 (IL-6), adiponectin and C reactive protein. Conclusion: LBP has the functions of decreasing serum glucose and reducing TNF-α in type 2 diabetic patients.

Key words: Lycium barbarum polysaccharide, type 2 diabetes, glucose

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