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The Hypolipidemic Mechanism of Proanthocyanidins

ZHANG Yu, LI Lanqi, GONG Hui, CHEN Shiguo, YE Xingqian   

  1. College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China
  • Online:2016-07-15 Published:2016-07-26
  • Contact: YE Xingqian

Abstract:

Proanthocyanidins are a class of polyphenols that consist of flavan-3-ols as their basic unit and exist in various
types of plants. In this review, the regulation of proanthocyanidins on the key proteins of the metabolism pathways of
triglycerides and cholesterol is summarized. Also, how proanthocyanidins regulate body weight, energy intake and energy
expenditure through adenosine 5’-monophosphate-activated protein kinase (AMPK) pathway to exert their hypolipidemic
effects is demonstrated with details as well.

Key words: proanthocyanidins, triglyceride, cholesterol, adenosine 5’-monophosphate-activated protein kinase (AMPK), metabolism

CLC Number: