Abstract:

Lipids, compounds with complex structures and classes, are one important class of biomacromolicules in organisms.
Abnormal lipid metabolisms may lead to many metabolic diseases, such as atherosclerosis. Lipidomics, a sub-branch of
metabonomics, is an important approach aiming at comprehensive analysis of lipid metabolisms. Recent advancements in mass
spectrometry combining with chromatography have led to the rapid development of lipidomics. Investigating the role of lipid
molecules in metabolic diseases has attracted increasing attention. In this review, we focus on the analytical approaches in used in
lipidomics research, and recent advances in their applications in the field of nutrition and health.

Key words: lipidomics, progress, metabolic disease, nutrition