Abstract:

In recent years, women’s health problems caused by estrogen metabolic disorder have drawn great public
attention. Some studies show that the gut microbiota has a significant impact on the host estrogen metabolism and its
metabolites. The application of probiotics can improve the intestinal microbiota by promoting the growth of beneficial
bacteria, thereby improving the estrogen metabolism in the body. Besides, probiotics can regulate the host blood circulation,
thus improving a wide spectrum of estrogen metabolism-related disorders. This paper reviews the current knowledge of
probiotics in relation to estrogen-related diseases, as well as the clinical application of probiotics in preventing and treating
estrogen metabolic disorders.

Key words: probiotics, gut microbiota, estrogen, estrogen metabolic disorders