FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (23): 40-43.doi: 10.7506/spkx1002-6630-201023010

• Basic Research • Previous Articles     Next Articles

Anti-aging Effect of Antioxidant Peptides from Rice Bran

FAN Jin-juan1，FU Yan-song1，ZONG Li-li3， ZHANG Xin-yu2，LUO Xia1，ZHU Yan-shu1   

  1. 1. College of Biotechnology, Shenyang Agricultural University, Shenyang 110866, China；
    2. Institute of Geographical Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China；
    3. College of Agricultural, Jilin Agricultural University, Changchun 130118, China
  • Received:2010-03-31 Revised:2010-11-04 Online:2010-12-15 Published:2010-12-29
  • Contact: FAN Jin-juan E-mail:jinjuanf@hotmail.com

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Abstract:

The D-galactose (D-gal)-induced aging model mice were used to explore the effects of antioxidant peptides from rice bran on the activities of catalase (CAT), glutathione peroxidase (GSH-Px), succinate dehydrogenase (SDH) and total adenosine triphosphatase (T-ATPase) in mitochondria of heart and brain and on deletion mutation of mitochondria DNA (mtDNA) in brain by polymerase chain reaction (PCR) and photodensity scan. Results indicated that rice bran antioxidant peptides at the condition of high dosage could significantly increase the activities of CAT, GSH-Px, SDH and T-ATPase in mitochondria of heart and brain (P ＜ 0.05); and significantly decrease the depletion of mtDNA in brain (P ＜ 0.01) of D-gal-induced-aging mice when compared with the model group. These investigations suggest that rice bran antioxidant peptides are able to enhance antioxidant function of aging mice induced by D-gal, and have good protective effect on mtDNA.

Key words: rice bran antioxidant peptides, mitochondrial DNA (mtDNA), anti-aging

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