FOOD SCIENCE ›› 2010, Vol. 31 ›› Issue (23): 360-365.doi: 10.7506/spkx1002-6630-201023080

• Nutrition & Hygiene • Previous Articles     Next Articles

Evaluation of Immunoregulatory Function of Formula Milk Powder Added with Lactoprotein Hydrolysates

MENG Wei-bin1, HU Zhi-he1,*, WANG Li-juan1, FENG Yong-qiang2, ZHU Li-min2   

  1. 1.Tianjin Key Laboratory of Food Biotechnology, College of Biotechnology and Food Science, Tianjin University of
    Commerce, Tianjin 300134, China;2. Tianjin Haihe Dairy Co. Ltd., Tianjin 300402, China
  • Received:2010-06-27 Revised:2010-11-10 Online:2010-12-15 Published:2010-12-29
  • Contact: HU Zhi-he E-mail:hzhihe@tjcu.edu.cn

Abstract:

To understand the immunoregulatory function of formula milk powder added with lactoprotein hydrolysates, different doses of infant formula milk powder and middle-aged and senior formula milk powder with and without the additions of casein and milk whey protein hydrolysates were orally administered to the Balb/c mouse model with immunosuppression induced by intraperitoneal injection of cyclophosphate (Cy) for 15 successive days, respectively. Spleen index, thymus index, cellular immune response, humoral immune function and phagocytic function of mononuclear macrophage were determined on the second day after the last administration. It was found that the evaluation results of infant formula milk powder and middleaged and senior formula milk powder added with lactoprotein hydrolysates were both positive, thus proving that adding lactoprotein hydrolysates enhances the immunoregulatory function of formula milk powder.

Key words: lactoprotein hydrolysates, formula milk powder, immunoregulatory function

CLC Number: