食品科学 ›› 2009, Vol. 30 ›› Issue (21): 428-431.doi: 10.7506/spkx1002-6300-200921100

• 专题论述 • 上一篇    下一篇

姜黄素对化学物神经毒性的保护作用研究进展

赵小武1,杜春明1,陆荣柱1 ,* ,高坚瑞1,欧阳臻2   

  1. 1.江苏大学基础医学与医学技术学院预防医学教研室 2.江苏大学药学院生药系
  • 收稿日期:2008-11-10 修回日期:2009-07-05 出版日期:2009-11-01 发布日期:2010-12-29
  • 通讯作者: 陆荣柱 E-mail:lurz@ujs.edu.cn
  • 基金资助:

    国家自然科学基金项目(30872139);江苏大学营养与疾病科研团队基金项目;
    江苏大学大学生科研立项及实践创新训练计划项目

Nneuroprotective Effects of Curcumins: An Overview

ZHAO Xiao-wu1,DU Chun-ming1,LU Rong-zhu1,*,GAO Jian-rui1,OUYANG Zhen2   

  1. 1. Staff Room of Preventive Medicine, School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang 212013,
    China;2. Department of Herbal Medications, School of Pharmacy, Jiangsu University, Zhenjiang 212013, China
  • Received:2008-11-10 Revised:2009-07-05 Online:2009-11-01 Published:2010-12-29
  • Contact: LU Rong-zhu E-mail:lurz@ujs.edu.cn

摘要:

姜黄素是一类具有抗氧化、抗炎以及抗肿瘤等多重药理作用的食用植物性色素。本文综合分析姜黄素对化学物神经毒性的保护作用、研究方法以及可能的作用机制,为姜黄素类植物化学物的开发以及相关化学物接触人群的化学预防提供参考。

关键词: 姜黄素, 神经毒性, 神经毒性化学物, 神经保护

Abstract:

Curcumins are a class of edible yellow pigments from rhizome of Curcuma longa Linn with multiple pharmacological functions, including anti-oxidation, anti-inflammation and anti-cancer. In this overview, neuroprotection effects of curcumins, research approaches and potential mechanisms are comprehensively summarized, which will provide valuable information for the development of curcumin-related health care products and the chemoprevention of neurotoxic damage.

Key words: curcumins, neurotoxicity, neurotoxic chemicals, neuroprotection

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