食品科学 ›› 2011, Vol. 32 ›› Issue (9): 303-306.doi: 10.7506/spkx1002-6630-201109067

• 专题论述 • 上一篇    下一篇

乳酸菌抗肿瘤作用研究进展

袁起伟,郝凤奇,杨文涛杨桂连*,王春凤   

  1. 1.吉林农业大学动物科学技术学院 2.长春理工大学生命科学技术学院
  • 出版日期:2011-05-15 发布日期:2011-04-11
  • 基金资助:
    国家“863”计划项目(2006AA10A205;2007AA10Z322);国家自然科学基金项目(30671573;30700602; 30870116);吉林省科技发展计划项目(20080104)

Research Progress on Anti-tumor Activity of Lactic Acid Bacteria

YUAN Qi-wei1,HAO Feng-qi2,YANG Wen-tao1,YANG Gui-lian1,*,WANG Chun-feng1   

  1. 1. College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China; 2. College of Life Science and Technology, Changchun University of Science and Technology, Changchun 130022, China
  • Online:2011-05-15 Published:2011-04-11

摘要: 乳酸菌是人体消化道内正常菌群之一,已在世界范围内被认为是“GRAS(generally regarded as safe)”等级的食品微生物。乳酸菌通过阻止有害菌的定植与侵袭、激活机体抗肿瘤免疫系统、干扰肿瘤细胞代谢促进其凋亡等多种功能对多种肿瘤有预防与治疗作用。研究乳酸菌的抗肿瘤作用对肿瘤生物防治技术的进步和加快抗肿瘤药物的升级换代具有重要意义。

关键词: 乳酸菌, 抗肿瘤, 抗肿瘤药物

Abstract: The gastrointestinal tract is a complex environment with a diverse microbial community and the probiotic lactic acid bacteria is among the normal flora. Probiotics have been shown to promote the intestinal barrier function and immune responses and to interfere with metabolism of tumor cells, preventing and treating a variety of cancers. The development of biological agents of lactic acid bacteria with the effect of anti-tumor is the foundation of enhancing the biological anti-cancer technology and accelerating the drug upgrading for cancer treatment.

Key words: lactic acid bacteria, anti-tumor, anti-cancer drugs

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