关键词: 多糖, 炎症性肠病, 营养干预

Abstract: Polysaccharides are biologically active macromolecules present in many plants. Inflammatory bowel disease causes extensive damage to the colon and disrupts immune system homeostasis. Although drugs can alleviate inflammatory bowel disease to some extent, many of them can cause adverse reactions in clinical practice. Polysaccharides have been shown to prevent or mitigate colon damage and immune system disorders caused by inflammatory bowel disease. In this article, recent advances in understanding the protective effects and molecular mechanisms of food-derived natural polysaccharides against inflammatory bowel disease are reviewed, which will hopefully provide a theoretical rationale for the prevention of inflammatory bowel disease and the mechanistic exploration of nutrition intervention strategies.

Key words: polysaccharide, inflammatory bowel disease, nutrition intervention