食品科学 ›› 2019, Vol. 40 ›› Issue (21): 288-294.doi: 10.7506/spkx1002-6630-20181114-156

• 专题论述 • 上一篇    下一篇

芹菜素对神经细胞保护作用研究进展

孙胜楠,张友源,金少瑾,朱云峰,徐翠翠,马莺,卢卫红   

  1. (1.哈工大机器人(山东)智能装备研究院,生物健康工程研究所,山东 济南 250200;2.哈尔滨工业大学化工与化学学院,黑龙江 哈尔滨 150090)
  • 出版日期:2019-11-15 发布日期:2019-12-02
  • 基金资助:
    “十三五”国家重点研发计划重点专项(2017YFC1601900)

Recent Advances in Understanding Neuroprotective Effect of Apigenin

SUN Shengnan, ZHANG Youyuan, JIN Shaojin, ZHU Yunfeng, XU Cuicui, MA Ying, LU Weihong   

  1. (1. Biohealth Engineering Institute, HRG (Shandong) Intelligent Equipment Research Institute, Jinan 250200, China; 2. School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150090, China)
  • Online:2019-11-15 Published:2019-12-02

摘要: 芹菜素属于黄酮类化合物,广泛存在于多种蔬菜、水果、豆类和茶叶中。芹菜素能够透过血脑屏障发挥神经保护作用,改善神经系统疾病。本文主要从抗氧化、抗炎两方面阐述和探讨芹菜素神经保护作用机制及其在各种神经系统疾病中的改善作用,为芹菜素在此类疾病中的潜在应用提供新的思路和依据。

关键词: 芹菜素, 神经保护作用, 抗氧化, 抗炎, 作用机制

Abstract: Apigenin, a member of the flavone family, is ubiquitous in fruits, vegetables, beans and tea. Apigenin can pass through the blood-brain barrier and has a strong ability to protect the nervous system and attenuate relevant diseases. This review focuses on the neuroprotective mechanism of apigenin and its role in improving neurological diseases from antioxidant and anti-inflammation perspectives, which will provide new ideas and evidence for the potential application of apigenin in treating neurological diseases.

Key words: apigenin, neuroprotective effect, antioxidant, anti-inflammation, mechanism of action

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