FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (8): 294-296.

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Screen of Optimum Broth of Paecilomyces cicadae for Producing Hyaluronic Acid

 TAN  Ai-Juan, WU  Li-Kun, YU  Xiao-Bei   

  1. College of Life Science, Guizhou University, Guiyang 550025, China
  • Online:2007-08-15 Published:2011-10-24

Abstract: The effects of carbon source, nitrogen source and mineral salt on hyaluronic acid (HA) concentration in Paecilomyces cicadae broth were determined by the method of sulfuric acid carbazole. The results showed that the optimum liquid medium formula of Paecilomyces cicadae for producing HA is lactose (6%), mixture of beef extract (0.5%) and yeast extract(at the ratio of 1:1) and MgSO4·7H2O (0.1%).

Key words: Paecilomyces cicadae, hyaluric acid, culture medium, sulfuric acid carbazole